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Resolution of severe hyperglycemia by a balanced low-calorie diet in type 2 diabetes

1 Department of Diabetes and Clinical Endocrinology, Chellaram Diabetes Institute, Pune, Maharashtra, India
2 Department of Medical Nutrition, Chellaram Diabetes Institute, Pune, Maharashtra, India

Correspondence Address:
AG Unnikrishnan,
Chellaram Diabetes Institute, Lalani Quantum, Pune Bengaluru Highway, Bavdhan, Pune 411 021, [email protected]
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-019X.151799


Type 2 diabetes is a progressive disease with irreversible beta cell failure. Normalization of hyperglycemia following bariatric surgery and very low-calorie diet (<800 Kcal/day) has been reported. But these modalities are not readily acceptable to a large number of patients. Use of a moderately low calorie diet for regression of hyperglycemia in patients with type 2 diabetes has not been reported from India. We report a case of a gentleman with type 2 diabetes of 5 years duration achieving the regression of hyperglycemia by an low calorie diet. There was a reduction of hemoglobin A1c from 10.1% to 6.5% without medications. There was also an improvement in liver transaminases, triglycerides, and normalization of blood pressure without antihypertensive medications. He had improvement in markers of insulin resistance and secretion. Though these results do not suggest permanent cure of diabetes, they re-emphasizes the powerful effect of moderate dietary restriction regimen on glycemic improvements in compliant subjects.

Keywords: Exercise, low-calorie diet, regression, reversal, type 2 diabetes

How to cite this URL:
Bhatt AA, Mashelkar TS, Kukade GA, Unnikrishnan A G. Resolution of severe hyperglycemia by a balanced low-calorie diet in type 2 diabetes. J Med Nutr Nutraceut [Epub ahead of print] [cited 2023 Dec 6]. Available from: http://www.jmnn.org/preprintarticle.asp?id=151799



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